Porous silicon oxide–PLGA composite microspheres for sustained ocular delivery of daunorubicin

Carbamazepine-Loaded Porous Microspheres for Short-Term Sustained Drug Delivery

The present investigation is aimed to prepare the porous microspheres of carbamazepine using eudragit as release retardant, compritol as core forming agent, and HPMC as re-crystallization inhibitor for short-term sustained delivery of carbamazepine. The proposed microspheres were formulated using the emulsion solvent diffusion method. The obtained microspheres were characterized for its particl...

Porous Microspheres for Drug Delivery and Methods for Making Same

Hyaluronan microspheres for sustained gene delivery and site-specific targeting.

Hyaluronan is a naturally occurring polymer that has enjoyed wide successes in biomedical and cosmetic applications as coatings, matrices, and hydrogels. For controlled delivery applications, formulating native hyaluronan into microspheres could be advantageous but has been difficult to process unless organic solvents are used or hyaluronan has been modified by etherification. Therefore, we pre...

Albumin Microspheres as an Ocular Delivery System for Pilocarpine Nitrate

Pilocarpine nitrate loaded egg albumin microspheres were prepared by thermal denaturation process in the size range of 1-12 mum. A series of batches were prepared to study factors, which may affect the size and entrapment efficiency of drug in microspheres and optimized the process. Drug loaded microspheres so obtained were evaluated for their size, entrapment efficiency, release rate and biolo...

Optical characterization of porous silicon monolayers decorated with hydrogel microspheres

UNLABELLED The optical response of porous silicon (pSi) films, covered with a quasi-hexagonal array of hydrogel microspheres, to immersion in ethanol/water mixtures was investigated. For this study, pSi monolayers were fabricated by electrochemical etching, stabilized by thermal oxidation, and decorated with hydrogel microspheres using spin coating. Reflectance spectra of pSi samples with and w...